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Volume 7
Main Index

Issue 1


Syntheses of 5-Trifluoromethyluracil and 5-Trifluoromethyl-2′-deoxyuridine
Charles Heidelberger, David G. Parsons, and David C. Remy
pp 1 - 5; DOI:
10.1021/jm00331a001
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Pyrimidine Derivatives. V. Synthesis of Substituted Pyrimidines from 4-Amino-6-chloro-2-methylthiopyrimidine1-3
Mervyn Israel, Heljo Kangur Protopapa, Herbert N. Schlein, and Edward J. Modest
pp 5 - 10; DOI:
10.1021/jm00331a002
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Derivatives of Purinethiols. Purine Thiolcarbonates and Related Compounds
Elizabeth Dyer and Howard S. Bender
pp 10 - 14; DOI:
10.1021/jm00331a003
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1,4-Bismethanesulfonates of the Stereoisomeric Butanetetraols and Related Compounds
Peter W. Feit
pp 14 - 17; DOI:
10.1021/jm00331a004
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Vitamin B6 Analogs. II.1,2 Synthesis of 4,6-Dimethyl-5-mercapto-3-pyridinemethanol and of 5-Mercapto-6-methyl-3,4-pyridinedimethanol Hydrochlorides
Joseph L. Greene and John A. Montgomery
pp 17 - 20; DOI:
10.1021/jm00331a005
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Vitamin B6 Analogs. III. Some 5-Aminomethyl and 5-Thiomethyl Derivatives of Pyridoxine and 4-Desoxypyridoxine
Joseph L. Greene, Alice M. Williams, and John A. Montgomery
pp 20 - 23; DOI:
10.1021/jm00331a006
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Analogs of Tetrahydrofolic Acid. X.1,2 Synthetic and Enzymic Studies on the Contribution of the p-Aminobenzoyl-L-glutamate Moiety of Pyrimidyl Analogs to Binding to Some Folic Cofactor Area Enzymes
B. R. Baker, Daniel V. Santi, Prabodh I. Almaula, and William C. Werkheiser
pp 24 - 30; DOI:
10.1021/jm00331a007
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Derivatives of Fluorene. XVIII. New Halogenofluorenes. I. Potential Antitumor Agents
Hsi-lung Pan and T. Lloyd Fletcher
pp 31 - 38; DOI:
10.1021/jm00331a008
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Organic Disulfides and Related Substances. IX.1a Symmetrical Aminothiolsulfonates as Antiradiation Drugs1b
Lamar Field, Aldo Ferretti, R. R. Crenshaw, and Terence C. Owen
pp 39 - 44; DOI:
10.1021/jm00331a009
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The Stability of Tepa and Other Aziridine Chemosterilants
Morton Beroza and Alexej B. Bořkovec
pp 44 - 49; DOI:
10.1021/jm00331a010
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The Synthesis of 9-Citrulline, 9-Histidine, and 9-Desarginine Bradykinin
H. A. DeWald and E. D. Nicolaides
pp 50 - 53; DOI:
10.1021/jm00331a011
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Thyromimetics. III. The Synthesis and Relative Thyromimetic Activities of Some 4′-Ethers of Iodinated Thyronines and Thyroalkanoic Acids
Benjamin Blank, Cyrus M. Greenberg, and James F. Kerwin
pp 53 - 56; DOI:
10.1021/jm00331a012
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Synthesis and Properties of the Analgesic DL-α-1,3-Dimethyl-4-phenyl-4-propionoxyazacycloheptane (Proheptazine)
Julius Diamond, William F. Bruce, and Floyd T. Tyson
pp 57 - 60; DOI:
10.1021/jm00331a013
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Pyrrolidines. IX. 3-Aryl-3-pyrrolidinols
William A. Gould, Paul M. Lish, Yao-Hua Wu, Herbert R. Roth, Walter G. Lobeck, James M. Berdahl, and Rolland F. Feldkamp
pp 60 - 67; DOI:
10.1021/jm00331a014
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Enamine Derivatives of Malonic Acid with Pharmacologic Activities
Arthur A. Santilli, William F. Bruce, and T. S. Osdene
pp 68 - 72; DOI:
10.1021/jm00331a015
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Cyclic Analogs and Congeners of Succinyl Dicholine
John F. McCarthy, Joseph G. Cannon, Joseph P. Buckley, and William J. Kinnard
pp 72 - 75; DOI:
10.1021/jm00331a016
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Quaternary Ammonium Compounds. V. Antiacetylcholinesterase Activity of a Series of N-t-Alkylpyridinium Compounds
J. Thomas and W. Marlow
pp 75 - 77; DOI:
10.1021/jm00331a017
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Spiranes. IV. Alkyl, Cycloalkyl, Alkenyl, Aryl, Aralkyl, and Hydrazono Azaspirane Derivatives
Charles H. Grogan, Charles F. Geschickter, and Leonard M. Rice
pp 78 - 87; DOI:
10.1021/jm00331a018
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Anticonvulsants. I. Dibenzo[a,d]cycloheptadiene-5-carboxamide and Related Compounds
M. A. Davis, Stanley O. Winthrop, R. A. Thomas, F. Herr, Marie-Paule Charest, and Roger Gaudry
pp 88 - 94; DOI:
10.1021/jm00331a019
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The Anticonvulsant Activity of 3-Acylindoles Compared with Phenobarbital
H. H. Keasling, R. E. Willette, and J. Szmuszkovicz
pp 94 - 96; DOI:
10.1021/jm00331a020
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Preparation and Hypoglycemic Activity of Some 3,5-Disubstituted Hydantoins
Joseph G. Lombardino and Clifford F. Gerber
pp 97 - 101; DOI:
10.1021/jm00331a021
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The Antidiabetic Activity of 3,5-Dimethylpyrazoles
John B. Wright, William E. Dulin, and John H. Markillie
pp 102 - 105; DOI:
10.1021/jm00331a022
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Derivatives of Morphine. III.1 Sulfur Analogs of 14-Hydroxydihydrocodeinone
Frederic E. Stynler and Ulrich Weiss
pp 105 - 106; DOI:
10.1021/jm00331a023
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4,4,6,16α-Tetramethyl-5-androstenes
Susumu Nakanishi
pp 106 - 108; DOI:
10.1021/jm00331a024
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16α-Fluorinated Steroids from the Reaction of Perchloryl Fluoride with Enamides
Susumu Nakanishi
pp 108 - 110; DOI:
10.1021/jm00331a025
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A Tautomer of a 2-Thienol Analog of Stilbestrol
W. R. Biggerstaff, Henri Arzoumanian, and Kenneth L. Stevens
pp 110 - 113; DOI:
10.1021/jm00331a026
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Hypocholesteremic Agents. I. Pyridyl Carbinols
H. B. Wright, D. A. Dunnigan, and U. Biermacher
pp 113 - 115; DOI:
10.1021/jm00331a027
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Hexahydropyrimidines. IV.1 Synthesis of 2-[4-(N,N-Bis(2-chloroethyl)amino)aryl]-1,3-bis-(aralkyl) hexahydropyrimidines as Antitumor Agents2
John H. Billman and John L. Meisenheimer
pp 115 - 117; DOI:
10.1021/jm00331a028
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7-Aminodesacetoxycephalosporanic Acid and Its Derivatives
R. J. Stedman, K. Swered, and J. R. E. Hoover
pp 117 - 119; DOI:
10.1021/jm00331a029
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Hypocholesterolemic Agents. IV.1 3α-Methoxy-5α-androstane Derivatives
R. E. Counsell and P. D. Klimstra
pp 119 - 121; DOI:
10.1021/jm00331a030
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Synthesis of the Three Isomeric 7-Pyridylbenz(a)anthracenes
F. A. Vingiello, E. B. Ellerbe, T. J. Delia, and J. Yanez
pp 121 - 121; DOI:
10.1021/jm00331a031
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α-Alkyloximinocarboxamides for Biological Testing
Dominick A. Coviello
pp 121 - 121; DOI:
10.1021/jm00331a032
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Newer Methods in Preparative Organic Chemistry.
Donald J. Abraham
pp 122 - 122; DOI:
10.1021/jm00331a033
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Advances in Organic Chemistry. Methods and Results.
Alfred Burger
pp 122 - 122; DOI:
10.1021/jm00331a034
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Histo-Enzymologie des Glandes Endocrines.
Alfred Burger
pp 122 - 122; DOI:
10.1021/jm00331a035
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Hallucinogenic Drugs and their Psychotherapeutic Use.
Harvey M. Zelnick
pp 122 - 122; DOI:
10.1021/jm00331a036
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Issue 2


Pentazocine.1 Strong Analgesics and Analgesic Antagonists in the Benzomorphan Series2
S. Archer, N. F. Albertson, L. S. Harris, Anne K. Pierson, and J. G. Bird
pp 123 - 127; DOI:
10.1021/jm00332a001
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Some Potent Morphine Antagonists Possessing High Analgesic Activity
Marshall Gates and Thomas A. Montzka
pp 127 - 131; DOI:
10.1021/jm00332a002
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3-Alkyl-1,3-thiazane Derivatives and Precursors as Antiradiation Agents
E. Campaigne and P. K. Nargund
pp 132 - 135; DOI:
10.1021/jm00332a003
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The Synthesis and Preliminary Pharmacology of Some 9H-Pyrido[3,4-b]indoles (β-Carbolines)1 and Tryptamines Related to Serotonin and Melatonin2
Robert G. Taborsky and William M. McIsaac
pp 135 - 141; DOI:
10.1021/jm00332a004
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Acyltryptamines. III. 5-Acetyltryptophan and Related Compounds
Maximilian Von Strandtmann, Chester Puchalski, and John Shavel
pp 141 - 146; DOI:
10.1021/jm00332a005
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Investigations in Heterocycles. XV. Methylphenidate: A Versatile Intermediate in the Synthesis of Bicyclic Heterocycles with a Bridgehead Nitrogen Atom
George DeStevens and Marcel Bernier
pp 146 - 149; DOI:
10.1021/jm00332a006
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Synthesis of 6-Substituted Nicotinic Acid Derivatives as Analogs of Ergot Alkaloids
Jacob Lehrfeld, Allan M. Burkman, and James E. Gearien
pp 150 - 154; DOI:
10.1021/jm00332a007
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4-Alkyl- (or Aralkyl) 1-Aryl-2-piperazinones
Otis E. Fancher, Shin Hayao, and Wallace G. Strycker
pp 154 - 158; DOI:
10.1021/jm00332a008
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The Metabolism of Carbazole in Rats and Rabbits
S. R. Johns and S. E. Wright
pp 158 - 161; DOI:
10.1021/jm00332a009
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A Series of Coumarin Derivatives with Central Stimulating Activity
P. Da Re, G. Bonola, and L. Verlicchi
pp 162 - 166; DOI:
10.1021/jm00332a010
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The Anticonvulsant Activities of Some Substituted Acetonaphthones
W. H. Hunter, R. M. Quinton, P. H. Sherman, C. R. Worthing, and R. J. Boscott
pp 167 - 174; DOI:
10.1021/jm00332a011
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Thiocarbamate Derivatives of 2-Methyl-2-propyl-1,3-propanediol
B. J. Ludwig, Frank J. Stiefel, L. S. Powell, and Julius Diamond
pp 174 - 177; DOI:
10.1021/jm00332a012
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Central Nervous System Depressants. V. Polyhydroxy and Methoxyphenyl Ketones, Carbinols, and Derivatives
Robert Bruce Moffett, A. R. Hanze, and Patrick H. Seay
pp 178 - 186; DOI:
10.1021/jm00332a013
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Antitumor Activity and Structural Relationships of Purine Derivatives and Related Compounds against Neoplasms in Experimental Animals
Roland K. Robins
pp 186 - 199; DOI:
10.1021/jm00332a014
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The Preparation and Antitumor Properties of Acylated Derivatives of 6-Thiopurine Ribosides
Leland R. Lewis, Roland K. Robins, and C. C. Cheng
pp 200 - 204; DOI:
10.1021/jm00332a015
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Aminonucleosides. II.1 3′-Amino-3′-deoxyinosine and 3′-Amino-3′-deoxyadenosine 1-N-Oxide
Nancy Nichols Gerber
pp 204 - 207; DOI:
10.1021/jm00332a016
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Pyrimidines. II. Synthesis of 6-Fluorouracil
Iris Wempen and Jack J. Fox
pp 207 - 209; DOI:
10.1021/jm00332a017
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Synthesis of Potential Antineoplastic Agents. X. Preparation and Reactions of Aldehydes Related to Benzaldehyde Mustard1-3
Frank D. Popp
pp 210 - 212; DOI:
10.1021/jm00332a018
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Alkylating Agents Derived from Indole. IV. Synthesis of the 5-Nitrogen Mustard of Indole-3-carboxylic Acid
Joseph DeGraw and Leon Goodman
pp 213 - 215; DOI:
10.1021/jm00332a019
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Fluorine-Containing Potential Anticancer Agents. II.1a Syntheses of Some Trifluoromethylpurines and Trifluoromethylthiazolopyrimidines1b
Hideo Nagano, Shoji Inoue, Andrew J. Saggiomo, and Edward A. Nodiff
pp 215 - 220; DOI:
10.1021/jm00332a020
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Hydrazino Acids. II. Alkyl-, Aralkyl-, and Hydroxyalkyl-α-hydrazino Acids
G. Pollak, H. Yellin, and A. Carmi
pp 220 - 224; DOI:
10.1021/jm00332a021
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Phosphorylated Alkylating Agents Related to DL-Phenylalanine
Abelardo P. Martinez, William W. Lee, and Leon Goodman
pp 224 - 228; DOI:
10.1021/jm00332a022
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Analogs of Parasympathetic Neuroeffectors. I. Acetylselenocholine, Selenocholine, and Related Compounds
Wolfgang H. H. Günther and Henry G. Mautner
pp 229 - 232; DOI:
10.1021/jm00332a023
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Synthesis of A New Class of Antishock Agents
Richard E. Brown, David M. Lustgarten, R. John Stanaback, Melville W. Osborne, and Robert I. Meltzer
pp 232 - 235; DOI:
10.1021/jm00332a024
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Reaction of 6-Chloro-2-chloromethyl-4-phenylquinazoline 3-Oxide with Dimethylamine
S. Farber, H. M. Wuest, and R. I. Meltzer
pp 235 - 237; DOI:
10.1021/jm00332a025
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Structural Changes and Anticholinergic Activity in a Class of Tropic and α-Methyltropic Acid Derivatives
Veniero Scarselli, Giorgio Cignarella, and Giulio Maffii
pp 237 - 238; DOI:
10.1021/jm00332a026
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Steroidal Heterocycles. X.1 Steroidal[3,2-d]pyrimidines and Related Compounds
J. H. Ackerman, G. O. Potts, A. L. Beyler, and R. O. Clinton
pp 238 - 240; DOI:
10.1021/jm00332a027
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Some Substituted Pyrido(2,3)pyrazines
Irving A. Kaye
pp 240 - 241; DOI:
10.1021/jm00332a028
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2,6-Dialkylpiperazines. I. Synthesis of cis-2,6-Dimethylpiperazine Derivatives
Giorgio Cignarella
pp 241 - 242; DOI:
10.1021/jm00332a029
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p-Vinylphenyl Glycosides of Cellobiose and Maltose
A. Lionel Clingman
pp 242 - 243; DOI:
10.1021/jm00332a030
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Advances in Pharmacology.
Alfred Burger
pp 243 - 244; DOI:
10.1021/jm00332a031
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High Molecular Weight Substances in Human Urine.
Alfred Burger
pp 244 - 244; DOI:
10.1021/jm00332a032
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Outline of Pharmacology and Therapeutics.
Alfred Burger
pp 244 - 244; DOI:
10.1021/jm00332a033
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Medizin und Chemie.
Alfred Burger
pp 244 - 244; DOI:
10.1021/jm00332a034
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Issue 3


Semisynthetic Penicillins. I. 2-Biphenylylpenicillins
J. R. E. Hoover, A. W. Chow, R. J. Stedman, N. M. Hall, H. S. Greenberg, M. M. Dolan, and R. J. Ferlauto
pp 245 - 251; DOI:
10.1021/jm00333a001
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Semisynthetic Penicillins. II. Structure-Activity Studies on the 2-Biphenylyl Side Chain
R. J. Stedman, J. R. E. Hoover, A. W. Chow, M. M. Dolan, N. M. Hall, and R. J. Ferlauto
pp 251 - 255; DOI:
10.1021/jm00333a002
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New Antiviral Compounds with Considerable Activity in Vivo. IV. Aromatic α-Keto Aldehydes
G. Cavallini
pp 255 - 258; DOI:
10.1021/jm00333a003
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Synthesis and Muscle Relaxant Properties of 3-amino-4-arylpyrazoles
Elvin L. Anderson, John E. Casey, Leon C. Greene, John J. Lafferty, and Harry E. Reiff
pp 259 - 268; DOI:
10.1021/jm00333a004
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Antihypertensive Agents. II.1 3-Substituted 2H-1,2,4-Benzothiadiazine 1,1-Dioxides
John G. Topliss, Leroy M. Konzelman, Elizabeth P. Shapiro, Nathan Sperber, and Franklin E. Roth
pp 269 - 273; DOI:
10.1021/jm00333a005
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Enzyme Inhibitory Activity of 3-(2-Aminobutyl)indole Derivatives
J. B. Hester, M. E. Greig, W. C. Anthony, R. V. Heinzelman, and J. Szmuszkovicz
pp 274 - 279; DOI:
10.1021/jm00333a006
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A New Class of 5-Hydroxytryptamine Antagonists
Laszlo Gyermek
pp 280 - 284; DOI:
10.1021/jm00333a007
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Syntheses of Some 4-Hydroxycoumarins and Their Condensation Products with Aldehydes and Carboxylic Acids. The Anticoagulant Activity of Some 4-Hydroxycoumarin Derivatives
Mladen Deželić and Mladen Trkovnik
pp 284 - 288; DOI:
10.1021/jm00333a008
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β-Hydroxyphenethylamino Derivatives of Various Nitrogen Heterocycles
Donald E. Heitmeier and Allan P. Gray
pp 288 - 293; DOI:
10.1021/jm00333a009
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Synthesis and Antitussive Activity of a New Heterocyclic Ring System. Some 1,2-Diazabicyclo[2.2.2]octanes
P. M. Carabateas, A. R. Surrey, and L. S. Harris
pp 293 - 297; DOI:
10.1021/jm00333a010
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3-Alkyl-3-phenylpiperidine Derivatives as Analgesics
Hiroshi Kugita, Hirozumi Inoue, Toyonari Oine, Goro Hayashi, and Seiichi Nurimoto
pp 298 - 301; DOI:
10.1021/jm00333a011
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4-(β-Substituted ethyl)-3,3-diphenyl-2-pyrrolidinones. A New Series of CNS Stimulants
Carl D. Lunsford, Albert D. Cale, John W. Ward, Bernard V. Franko, and Herndon Jenkins
pp 302 - 310; DOI:
10.1021/jm00333a012
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6-Amino Derivatives of 5H-Dibenzo[d,f][1,3]diazepine
W. E. Kreighbaum and H. C. Scarborough
pp 310 - 312; DOI:
10.1021/jm00333a013
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Antidepressant Agents. Derivatives of 2,3-Polymethyleneindoles
Leonard M. Rice, Elisabeth Hertz, and Meier E. Freed
pp 313 - 319; DOI:
10.1021/jm00333a014
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Central Nervous System Depressants. VI. Polymethoxyphenyl Esters and Amides
Robert Bruce Moffett
pp 319 - 325; DOI:
10.1021/jm00333a015
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Desamino Analogs of Thyroxine
Annemarie Höfer and H. J. Cahnmann
pp 326 - 329; DOI:
10.1021/jm00333a016
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Hydroxylamine Chemistry. IV. O-Aralkylhydroxylamines
E. L. Schumann, R. V. Heinzelman, M. E. Greig, and W. Veldkamp
pp 329 - 334; DOI:
10.1021/jm00333a017
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π-Complexes with Biologically Significant Materials. III.1 Vitamin A Acetate Iron Tricarbonyl
Akira Nakamura and Minoru Tsutsui
pp 335 - 337; DOI:
10.1021/jm00333a018
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Potential Anticancer Agents. I. Schiff Bases and Hydrazone Derivatives of Pyrimidine-4-carboxaldehydes
Claude Piantadosi, Vilhjalmur G. Skulason, J. Logan Irvin, J. Meyers Powell, and Lynous Hall
pp 337 - 342; DOI:
10.1021/jm00333a019
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The Synthesis and Antiinflammatory Activity of Some Derivatives of 1,3-Diphenylbarbituric Acid
A. J. Vazakas and W. Walden Bennetts
pp 342 - 344; DOI:
10.1021/jm00333a020
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Synthesis and Anabolic Activity of 3-Methylene- and 3-Methylsteroids of the Androstane and 19-Norandrostane Series
K. Irmscher, H.-G. Kraft, and K. Brückner
pp 345 - 347; DOI:
10.1021/jm00333a021
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Synthesis and Biological Properties of Some Unique Cytotoxic Steroids
J. E. Pike, J. E. Grady, J. S. Evans, and C. G. Smith
pp 348 - 351; DOI:
10.1021/jm00333a022
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Synthesis of Pregn-4-eno[3,2-c]pyrazoles Related to 9α-Fluoro-16α-methylcortisol
Ralph Hirschmann, N. G. Steinberg, E. F. Schoenewaldt, W. J. Paleveda, and Max Tishler
pp 352 - 355; DOI:
10.1021/jm00333a023
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Synthesis of 2′-(2,4-Difluorophenyl)-11β,17,21-trihydroxy-6,16α-dimethyl-20- oxopregna-4,6-dieno[3,2-c]pyrazole
R. G. Strachan, N. G. Steinberg, Max Tishler, and Ralph Hirschmann
pp 355 - 355; DOI:
10.1021/jm00333a024
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17-Substituted 3β-Hydroxy-4-pregnen-20-ones
David J. Marshall, Peter F. Morand, Clara Revesz, and R. Gaudry
pp 355 - 357; DOI:
10.1021/jm00333a025
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A Nitrogen Mustard Derivative of 6-Mercaptopurine
Gershon Levin, Kanematsu Sugiura, and George Bosworth Brown
pp 357 - 358; DOI:
10.1021/jm00333a026
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Hydroxy-2-thiopyrimidine-5-carboxaldehyde Derivatives in Cancer Chemotherapy
Richard H. Wiley, Karl F. Hussung, W. E. Hobbs, and S. Huh
pp 358 - 359; DOI:
10.1021/jm00333a027
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Some Dichloroacetyl Derivatives and Their Antitumor Activity
Arthur Sweeny, Theodora N. Salmon, Abraham N. Fenster, Ihor Bekersky, and Judith Canter
pp 359 - 361; DOI:
10.1021/jm00333a028
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The Antileukemia Activity of Tylocrebrine
E. Gellert and R. Rudzats
pp 361 - 362; DOI:
10.1021/jm00333a029
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1,2-Disubstituted Naphth[2,3-d]imidazole-4,9-diones and Corresponding Quaternary Salts
Price Truitt, David Hayes, and Linda Truitt Creagh
pp 362 - 364; DOI:
10.1021/jm00333a030
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Pyridylurethanes of Pharmacological Interest
N. P. Buu-Hoï, Richard Rips, and Christian Derappe
pp 364 - 366; DOI:
10.1021/jm00333a031
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1,3,2-Diazaphosphorinane 2-Oxides. 1. Synthesis of Some 2-(N-Arylamino)-1,3,2-diazaphosphorinane 2-Oxides
John H. Billman, John L. Meisenheimer, and Richard A. Awl
pp 366 - 367; DOI:
10.1021/jm00333a032
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Monoamine Oxidase Inhibitors. Hydrazine Derivatives
Daniel Kaminsky, Bernard Dubnick, and Floyd E. Anderson
pp 367 - 369; DOI:
10.1021/jm00333a033
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The Synthesis of 2-Amino-3-trifluoromethylbutyric Acid
D. F. Loncrini and H. M. Walborsky
pp 369 - 370; DOI:
10.1021/jm00333a034
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para-Substituted Benzenesulfonylureas
Johann Lederer
pp 370 - 371; DOI:
10.1021/jm00333a035
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Insect Chemosterilants. I. N-Acylaziridines
C. W. Woods, A. B. Bořkovec, and F. M. Hart
pp 371 - 373; DOI:
10.1021/jm00333a036
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Insect Sex Attractants. V. The Synthesis of Some Additional Compounds Related to Gyplure
William A. Jones and Martin Jacobson
pp 373 - 374; DOI:
10.1021/jm00333a037
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Basically Substituted Derivatives of 4-Hydroxy-2,3,6-trimethoxy-5H-benzocyclohepten-5-one
John Krapcho
pp 374 - 375; DOI:
10.1021/jm00333a038
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Serotonin Inhibitors. II.1 2′-(3-Dimethylaminopropylthio)cinnamanilide and Related Compounds
John Krapcho, Ervin R. Spitzmiller, Chester F. Turk, and Josef Fried
pp 376 - 377; DOI:
10.1021/jm00333a039
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Oral Toxicity Study of 1,2,2-Trichloro-1,1,2-trifluoroethane
Joseph B. Michaelson and David J. Huntsman
pp 378 - 379; DOI:
10.1021/jm00333a040
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Analogs of Methyldopa and Dopa. Hydantoic Acids and Hydantoins
Ronald A. Vitali, Theodore A. Jacob, and John M. Chemerda
pp 379 - 381; DOI:
10.1021/jm00333a041
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Some Catalytic Hydrogenations in the Presence of Aryl Chloride
Morris Freifelder, Yew Hay Ng, and Preston F. Helgren
pp 381 - 382; DOI:
10.1021/jm00333a042
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The Identity of an Alleged Hypocholesteremic Agent Isolated from Bovine Pituitary
L. G. Humber and A. V. Marton
pp 382 - 383; DOI:
10.1021/jm00333a043
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Long-Chain Thiosemicarbazones as Potential Anticancer and Antiviral Agents
Benjamin Prescott and Chen Pein Li
pp 383 - 385; DOI:
10.1021/jm00333a044
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Nucleosides. IV. 1-(2-Deoxy-β-D-lyxofuranosyl)-5-iodouracil
Jerome P. Horwitz, Jonathan Chua, Michael Noel, and Margaret A. DaRooge
pp 385 - 386; DOI:
10.1021/jm00333a045
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5-Aryl-1,3-dihydro-2H-1,3,4-benzotriazepin-2-ones
Theodore S. Sulkowski and Scott J. Childress
pp 386 - 386; DOI:
10.1021/jm00333a046
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Quinazolines and 1,4-Benzodiazepines. XIX.1 N-Alkyl Derivatives of Substituted 1,3,4,5-Tetrahydro-5-phenyl-2H-1,4-benzodiazepin-2-ones
R. Ian Fryer, B. Brust, J. Earley, and L. H. Sternbach
pp 386 - 389; DOI:
10.1021/jm00333a047
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Derivatives of 2-(2-Pyrimidinyl)acetophenone
Frank F. Ebetino and E. D. Amstutz
pp 389 - 389; DOI:
10.1021/jm00333a048
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Synthesis of Some Derivatives of 5-Aminoindole-3-acrylic Acid
Joseph DeGraw and Leon Goodman
pp 389 - 390; DOI:
10.1021/jm00333a049
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Synthesis of Nortriptyline and Related Compounds
Lynn R. Peters and G. F. Hennion
pp 390 - 392; DOI:
10.1021/jm00333a050
PDF
Synthesis of a Cyclopropyl Carbinol in the Amitriptyline Series
R. D. Hoffsommer, D. Taub, and N. L. Wendler
pp 392 - 393; DOI:
10.1021/jm00333a051
PDF
Synthesis of 1,4-Naphthohydroquinone-2-carboxanilide and 1,4-Naphthoquinone-2-carboxanilide
Kenneth Swiatek and Stephen B. Binkley
pp 393 - 393; DOI:
10.1021/jm00333a052
PDF
Steroid Reactions: An Outline for Organic Chemists.
M. Alauddin
pp 393 - 394; DOI:
10.1021/jm00333a053
PDF
Spectrophotometric Analysis of Drugs Including Atlas of Spectra.
Robert E. Lyle
pp 394 - 394; DOI:
10.1021/jm00333a054
PDF
Physiologic Pharmacology.
Ruth R. Levine
pp 394 - 394; DOI:
10.1021/jm00333a055
PDF
Pharmaceutical Firms U. S. A. & Canada, 1964.
Alfred Burger
pp 394 - 394; DOI:
10.1021/jm00333a056
PDF

Issue 4


A Mathematical Contribution to Structure-Activity Studies
Spencer M. Free and James W. Wilson
pp 395 - 399; DOI:
10.1021/jm00334a001
PDF
The Metabolic Fate of Thiabendazole in Sheep
Dominick J. Tocco, Rudolf P. Buhs, Horace D. Brown, Alexander R. Matzuk, Holly E. Mertel, Robert E. Harman, and Nelson R. Trenner
pp 399 - 405; DOI:
10.1021/jm00334a002
PDF
Transformations of Eburicoic Acid. V.1 Cleavage of Ring A by the Fungus Glomerella fusarioides
Allen I. Laskin, Paul Grabowich, Carol De Lisle Meyers, and Josef Fried
pp 406 - 409; DOI:
10.1021/jm00334a003
PDF
Structures Related to Morphine. XXVII.1 α- and β-5,9-Diethyl-2-methyl-6,7-benzomorphans
Arthur E. Jacobson and Everette L. May
pp 409 - 412; DOI:
10.1021/jm00334a004
PDF
Analgetics Based on the Pyrrolidine Ring. III.
J. F. Cavalla, R. Jones, M. Welford, J. Wax, and C. V. Winder
pp 412 - 415; DOI:
10.1021/jm00334a005
PDF
Synthesis and Pharmacological Activity of 3-(2-Pyrrolidinyl)indoles
Gilbert A. Youngdale, Douglas G. Anger, William C. Anthony, John P. Da Vanzo, Margaret E. Greig, Richard V. Heinzelman, Hugh H. Keasling, and Jacob Szmuszkovicz
pp 415 - 427; DOI:
10.1021/jm00334a006
PDF
4-Aminomorpholines
Max J. Kalm
pp 427 - 433; DOI:
10.1021/jm00334a007
PDF
Behavioral and Neuropharmacological Actions of 3-Methyl-4-(1-phenyl-2-propylamino)-2-phenylmorpholine and Associated 4-Aminomorpholines
Donald L. Knapp
pp 433 - 439; DOI:
10.1021/jm00334a008
PDF
Anticonvulsants. II. Spiro Compounds. Dibenzo[α,d]cycloheptadiene-5,5′-hydantoins, -5,5′-oxazolidinediones, and -5,2′-succinimides
M. A. Davis, Stanley O. Winthrop, R. A. Thomas, F. Herr, Marie-Paule Charest, and Roger Gaudry
pp 439 - 445; DOI:
10.1021/jm00334a009
PDF
Central Nervous System Depressants. VII.1 Pyridyl Coumarins
Robert Bruce Moffett
pp 446 - 449; DOI:
10.1021/jm00334a010
PDF
Quaternary Salts of Triethylenediamine
Robert Bruce Moffett
pp 450 - 453; DOI:
10.1021/jm00334a011
PDF
Antihypertensive Agents. III.1 3-Hydroxy-3-phenylphthalimidines
John G. Topliss, Leroy M. Konzelman, Nathan Sperber, and Franklin E. Roth
pp 453 - 456; DOI:
10.1021/jm00334a012
PDF
Derivatives of 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene and Related Compounds. II
Frank J. Villani, Claire A. Ellis, Robert F. Tavares, and Catherine Bigos
pp 457 - 460; DOI:
10.1021/jm00334a013
PDF
A Viscometric Study of Hydrogen-Bonding Properties of Carcinogenic Nitrosamines and Related Compounds
Mary F. Argus, Joseph C. Arcos, Ashraful Alam, and Jerrell H. Mathison
pp 460 - 465; DOI:
10.1021/jm00334a014
PDF
The Synthesis of 4,5-Dimethyl-1,2-benzanthracene and 4,5,10-Trimethyl-1,2-benzanthracene
Melvin S. Newman and Shoshana Blum
pp 466 - 468; DOI:
10.1021/jm00334a015
PDF
Synthesis of N6,N6-Bis(2-chloroethyl)-DL-lysine
G. Vita, L. Monti, and R. Angelucci
pp 468 - 471; DOI:
10.1021/jm00334a016
PDF
Further Investigations of Heterocyclic Alkylating Agents
Robert K. Preston, Richard M. Peck, Evelyn R. Breuninger, Ann J. Miller, and Hugh J. Creech
pp 471 - 480; DOI:
10.1021/jm00334a017
PDF
Acridine and Quinoline Analogs of Nitrogen Mustard with Amide Side Chains
Richard M. Peck, Evelyn R. Breuninger, Ann J. Miller, and Hugh J. Creech
pp 480 - 482; DOI:
10.1021/jm00334a018
PDF
Derivatives of 6-Aminopenicillanic Acid. V. Synthesis of 6-Aminopenicillanyl Alcohol and Certain Derivatives
Y. G. Perron, L. B. Crast, J. M. Essery, R. R. Fraser, J. C. Godfrey, C. T. Holdrege, W. F. Minor, M. E. Neubert, R. A. Partyka, and L. C. Cheney
pp 483 - 487; DOI:
10.1021/jm00334a019
PDF
Synthetic Schistosomicides. V. N-(Mono- and dialkylaminoalkyl)-1,4-naphthalenediamines and Related Naphthylamines
Edward F. Elslager, David B. Capps, Leslie M. Werbel, Donald F. Worth, Jack E. Meisenhelder, and Paul E. Thompson
pp 487 - 493; DOI:
10.1021/jm00334a020
PDF
Synthesis and Biological Properties of Aminoalkylhydrazines. A Unique Nitrogen-Nitrogen Scission of 1-(2-Diethylaminoethyl)-2-(1-phenyl-2-propyl)hydrazine
Edward F. Elslager, Enta A. Weinstein, and Donald F. Worth
pp 493 - 500; DOI:
10.1021/jm00334a021
PDF
Agents Affecting Lipid Metabolism. VIII. N,N′-Dibenzylethylenediamine, the Key to a Novel Class of Cholesterol Biosynthesis Inhibitors
Michael Kraml, Leslie G. Humber, Jean Dubuc, and Roger Gaudry
pp 500 - 503; DOI:
10.1021/jm00334a022
PDF
The Effect of Substituted Carboxylic Acids on Hepatic Cholesterogenesis
Peter Morand, Jehan F. Bagli, Michael Kraml, and J. Dubuc
pp 504 - 508; DOI:
10.1021/jm00334a023
PDF
A Correlation of Drug Concentration with Sterol Biosynthesis Inhibition in the Liver
S. K. Figdor, E. C. Schreiber, R. B. Stebbins, P. F. Moore, and Rex Pinson
pp 508 - 510; DOI:
10.1021/jm00334a024
PDF
Some Hypocholesteremic 2,3-Diphenylacrylonitriles
G. M. K. Hughes, P. F. Moore, and R. B. Stebbins
pp 511 - 518; DOI:
10.1021/jm00334a025
PDF
Analogs of Steroid Hormones. I. 6-(4-Oxocyclohexenyl) and 6-(p-Hydroxyphenyl) Derivatives of 2-Naphthalenone
R. E. Juday, D. P. Page, and G. A. Du Vall
pp 519 - 524; DOI:
10.1021/jm00334a026
PDF
15-Oxygenated Progesterones. A New Series of Synthetic Mineralocorticoid Antagonists
Robert C. Tweit and C. M. Kagawa
pp 524 - 528; DOI:
10.1021/jm00334a027
PDF
Steroids. CCL.1 The Synthesis of 2-Methylenehydrocortisone2
J. A. Edwards, M. C. Calzada, and A. Bowers
pp 528 - 530; DOI:
10.1021/jm00334a028
PDF
Synthesis of Some Pregnane 16-Thioesters
Leland L. Smith and Daniel M. Teller
pp 531 - 537; DOI:
10.1021/jm00334a029
PDF
Some 20-Substituted 21-Norprogesterone Derivatives
D. F. Morrow, T. P. Culbertson, E. L. Wittle, M. E. Butler, and M. M. Creger
pp 537 - 539; DOI:
10.1021/jm00334a030
PDF
6,16-Dimethylated Steroids. II. Studies on the Synthesis of 6,16α-Dimethyl-17α-hydroxyprogesterones
Robert P. Graber, Martin B. Meyers, LeRoy G. Hickman, Eugene H. Borochoff, and Arthur D. Odell
pp 540 - 547; DOI:
10.1021/jm00334a031
PDF
6,16-Dimethylated Steroids. III. Synthesis of 21-Substituted 6,16α-Dimethyl-17α-hydroxyprogesterones
Martin B. Meyers, Robert P. Graber, and Duane A. Jones
pp 548 - 551; DOI:
10.1021/jm00334a032
PDF
6,16-Dimethylated Steroids. IV. 4,4-Dimethyl Analogs
Susumu Nakanishi and Robert P. Graber
pp 552 - 554; DOI:
10.1021/jm00334a033
PDF
Steroidal Thiazenones and Related Compounds
Philip E. Shaw, F. W. Gubitz, K. F. Jennings, G. O. Potts, A. L. Beyler, and Robert L. Clarke
pp 555 - 560; DOI:
10.1021/jm00334a034
PDF
A Silicon Analog of a Sympathomimetic Amine
Ralph J. Fessenden and Marvin D. Coon
pp 561 - 562; DOI:
10.1021/jm00334a035
PDF
Cyclopropane Analogs of Choline Ethers
Alfred Burger and Hans-Jørgen Petersen
pp 562 - 564; DOI:
10.1021/jm00334a036
PDF
Derivatives of 1-(5-Nitrofurfurylideneamino)hydantoin. Synthesis and Some Biological Properties
Feriano Banci, Ezio Tubaro, and Marcello Ferappi
pp 564 - 567; DOI:
10.1021/jm00334a037
PDF
The Anomeric 5-Allyl-2′-deoxyuridines
Harry J. Minnemeyer, Priscilla B. Clarke, Howard Tieckelmann, and James F. Holland
pp 567 - 569; DOI:
10.1021/jm00334a038
PDF
Preparation of D- and L-Octopamine
Thomas Kappe and Marvin D. Armstrong
pp 569 - 571; DOI:
10.1021/jm00334a039
PDF
4,4′-Dihydroxytriphenylacetic Acid
Max H. Hubacher
pp 571 - 571; DOI:
10.1021/jm00334a040
PDF
Aromatic Fluorine Compounds. XII. N-(Fluorophenyl) Carbamates
G. C. Finger, D. R. Dickerson, D. E. Orlopp, and J. W. Ehrmantraut
pp 572 - 573; DOI:
10.1021/jm00334a041
PDF
Testosterone 17-Heptanoate 3-Benziloylhydrazone
Clarence H. Gleason
pp 573 - 573; DOI:
10.1021/jm00334a042
PDF
Amides from Nitriles and Alcohols by the Ritter Reaction
John A. Sanguigni and Robert Levine
pp 573 - 574; DOI:
10.1021/jm00334a043
PDF
Substrates for Cytochemical Demonstration of Enzyme Activity. I. Some Substituted 3-Indolyl-β-D-glycopyranosides
Jerome P. Horwitz, Jonathan Chua, Ronald J. Curby, Arthur J. Tomson, Margaret A. Da Rooge, Benjamin E. Fisher, Jose Mauricio, and Irwin Klundt
pp 574 - 575; DOI:
10.1021/jm00334a044
PDF
Handbuch der Experimentellen Pharmakologie. Volume 15. Cholinesterases and Anticholinesterase Agents.
B. V. Rama Sastry and Milton T. Bush
pp 575 - 576; DOI:
10.1021/jm00334a045
PDF
Diuretics. Chemistry and Pharmacology.
Joseph Weinstock
pp 576 - 576; DOI:
10.1021/jm00334a046
PDF
International Pharmaceutical Abstracts.
Alfred Burger
pp 576 - 576; DOI:
10.1021/jm00334a047
PDF

Issue 5


The Steroid-Receptor Complex. Some Considerations Based on sp2-Hybridized Systems
Manfred E. Wolff, Winston Ho, and Russell Kwok
pp 577 - 584; DOI:
10.1021/jm00335a001
PDF
Heterocyclic Steroids in the Antiinflammatory Series
Helmut Mrozik, Paul Buchschacher, John Hannah, and John H. Fried
pp 584 - 589; DOI:
10.1021/jm00335a002
PDF
Heterocyclic Steroids. VI. Steroidal Pyridazones and Pyridazinones
D. M. Piatak, R. I. Dorfman, D. Tibbetts, and E. Caspi
pp 590 - 592; DOI:
10.1021/jm00335a003
PDF
Studies on the Aromatization of 10β-Hydroxy-3-keto Steroids
Rashad Y. Kirdani and Donald S. Layne
pp 592 - 595; DOI:
10.1021/jm00335a004
PDF
Rifamycins.1 XXXV.2 Amides and Hydrazides of Rifamycin B3
P. Sensi, N. Maggi, R. Ballotta, S. Fürész, R. Pallanza, and V. Arioli
pp 596 - 602; DOI:
10.1021/jm00335a005
PDF
D-Aspartyl1-valyl5-phenylalanine8 Amide Angiotensin II
Hans-Jürgen Hess and Jay W. Constantine
pp 602 - 606; DOI:
10.1021/jm00335a006
PDF
Synthetic Antigonadotropins. I. Triarylethylenes
H. H. Fox, J. T. Gibas, H. L. Lee, and A. Boris
pp 606 - 608; DOI:
10.1021/jm00335a007
PDF
Novel Polycyclic Heterocycles. II. Derivatives of 5,11-Dihydrodibenz[b,e][1,4]oxazepine
Harry L. Yale and Francis Sowinski
pp 609 - 614; DOI:
10.1021/jm00335a008
PDF
Synthesis and Biological Evaluation of Substituted β-Dimethylaminoethyl α-Phenyl-cis- and -trans-cinnamates
Vinod P. Shah and Roger Ketcham
pp 614 - 619; DOI:
10.1021/jm00335a009
PDF
4-Substituted Piperidines. I. Derivatives of 4-t-Amino-4-piperidinecarboxamides
Cornelis van de Westeringh, Paul Van Daele, Bert Hermans, Cyriel Van der Fycken, Jozef Boey, and Paul A. J. Janssen
pp 619 - 623; DOI:
10.1021/jm00335a010
PDF
Diphenylpropylamine Derivatives. I. N-Substituted 3,3-Diphenylpropylamines
K. Harsányi, D. Korbonits, and P. Kiss
pp 623 - 625; DOI:
10.1021/jm00335a011
PDF
Synthesis and in Vitro Activity of Some Aryl Diaziridines as Potential Monoamine Oxidase Inhibitors1a-c
Charles J. Paget and Charles S. Davis
pp 626 - 628; DOI:
10.1021/jm00335a012
PDF
Antidepressants.1 II. Derivatives of Polynuclear Indoles
Meier E. Freed, Elisabeth Hertz, and Leonard M. Rice
pp 628 - 632; DOI:
10.1021/jm00335a013
PDF
Synthesis and Microbiological Properties of 3-Amino-3,4-dihydro-1-hydroxycarbostyril
Alvie L. Davis, Ok Hi Park Choun, Drusilla E. Cook, and Tommy J. McCord
pp 632 - 634; DOI:
10.1021/jm00335a014
PDF
Isolation and Characterization of Urinary Metabolites of Benzquinamide and Benzquinamide Alcohol
B. Kenneth Koe and Rex Pinson
pp 635 - 640; DOI:
10.1021/jm00335a015
PDF
Synthesis and Biological Evaluation of Water-Soluble 2-Boronoethylthio Compounds
D. S. Matteson, A. H. Soloway, D. W. Tomlinson, J. D. Campbell, and G. A. Nixon
pp 640 - 643; DOI:
10.1021/jm00335a016
PDF
Ammonoacetals. I. A New Class of Potential Antineoplastic Compounds
T. P. Abbiss, A. H. Soloway, and V. H. Mark
pp 644 - 645; DOI:
10.1021/jm00335a017
PDF
Synthesis of Potential Antineoplastic Agents. XXXIII. β-Diketone Analogs of the Glutarimide Antibiotics
Robert F. Struck, Howard J. Schaeffer, Charles A. Krauth, Robert T. Kemp, Y. Fulmer Shealy, and John A. Montgomery
pp 646 - 650; DOI:
10.1021/jm00335a018
PDF
Polypeptides from p-Phenylalanine Mustard
Carol W. Mosher, Robert H. Iwamoto, Edward M. Acton, and Leon Goodman
pp 650 - 652; DOI:
10.1021/jm00335a019
PDF
N,N-Bis(2-chloroethyl)carbamoyl Derivatives of L-Amino Acids. New Potential Antitumor Agents with Latent Activity
Ezra Khedouri, Young-Ho Kim, and Orrie M. Friedman
pp 653 - 655; DOI:
10.1021/jm00335a020
PDF
The Preparation of Nucleosides from Allose, Altrose, Gulose, Talose, and Mannose
Leon M. Lerner and Paul Kohn
pp 655 - 658; DOI:
10.1021/jm00335a021
PDF
Synthetic Schistosomicides. VI. 4-Substituted 1-(Dialkylaminoalkylamino)naphthalenes
Edward F. Elslager, David B. Capps, and Leslie M. Werbel
pp 658 - 662; DOI:
10.1021/jm00335a022
PDF
Synthetic Schistosomicides. VII. 5-Azo-6-Alkoxy-8-(Aminoalkylamino)quinolines
Edward F. Elslager and David B. Capps
pp 663 - 664; DOI:
10.1021/jm00335a023
PDF
Hypocholesteremic Agents. II. The Hydrogenation of Some Pyridinesulfonic and Pyridinealkanesulfonic Acids
Morris Freifelder and Howard B. Wright
pp 664 - 665; DOI:
10.1021/jm00335a024
PDF
The Synthesis of N-Hydroxycarbanilides and Their Evaluation as Germicides
Peggy P. Hoffman, Richard K. Madison, and William B. Hardy
pp 665 - 668; DOI:
10.1021/jm00335a025
PDF
A Simple Method for Predicting the Carcinogenic Properties of Polycyclic Aromatic Molecules
R. L. Flurry
pp 668 - 670; DOI:
10.1021/jm00335a026
PDF
Cyano Analogs of Phenolic Nitrogen Mustards
William J. Burke, Joe E. Brown, Carl Weatherbee, and D. H. Curtis
pp 670 - 671; DOI:
10.1021/jm00335a027
PDF
Alkyl and Aryl Thiolsulfonates
James P. Weidner and Seymour S. Block
pp 671 - 673; DOI:
10.1021/jm00335a028
PDF
Antiviral Compounds. IX. Steroid Derivatives
G. Cavallini, E. Massarani, and D. Nardi
pp 673 - 675; DOI:
10.1021/jm00335a029
PDF
The Preparation of Penicilloyl-Polylysines, Skin Test Reagents for the Clinical Evaluation of Penicillin Hypersensitivity
Bernard B. Levine
pp 675 - 676; DOI:
10.1021/jm00335a030
PDF
2-Amino- and Substituted Aminomethyl-1,2,3,10b-tetrahydrafluoranthen-3-ones
S. Wawzonek and I. H. Petersen
pp 677 - 678; DOI:
10.1021/jm00335a031
PDF
Pteridinosteroids. II. Synthesis of 17β-Acetoxy-5α-androstano[2,3-g] -2′,4′-diaminopteridine
S. P. Raman, Z. F. Chmielewicz, and Thomas J. Bardos
pp 678 - 680; DOI:
10.1021/jm00335a032
PDF
Ethyl N-Benzylleucinate Nitrogen Mustard
Howard E. Smith and Susan L. Cook
pp 680 - 681; DOI:
10.1021/jm00335a033
PDF
C-19 Functional Steroids. VII.1 Desoxycorticosterone-19-nitrile Acetate
Manfred E. Wolff and Winston Ho
pp 681 - 682; DOI:
10.1021/jm00335a034
PDF
Anticholinesterase Activity of Phenylalkyltrimethylammonium Compounds
A. S. Hume and W. C. Holland
pp 682 - 684; DOI:
10.1021/jm00335a035
PDF
New Progestational Agents. Nonclassical 17-Alkylpregnene Structures
George R. Allen and Martin J. Weiss
pp 684 - 686; DOI:
10.1021/jm00335a036
PDF
Derivatives of 2-Hvdroxy-1,3,2-benzodioxastibole
L. Cortés, J. Mantecón, and G. Chuchani
pp 686 - 686; DOI:
10.1021/jm00335a037
PDF
Methyl Analogs of Papaverine
James G. Beasley and Alfred Burger
pp 686 - 689; DOI:
10.1021/jm00335a038
PDF
Isolation of Cephalosporin C
E. L. Patterson, J. C. Van Meter, and N. Bohonos
pp 689 - 689; DOI:
10.1021/jm00335a039
PDF
Vitamins and Coenzymes.
Alfred Burger
pp 689 - 689; DOI:
10.1021/jm00335a040
PDF
Science Citation Index.
Alfred Burger
pp 690 - 690; DOI:
10.1021/jm00335a041
PDF
Progress in Drug Research.
Alfred Burger
pp 690 - 690; DOI:
10.1021/jm00335a042
PDF
Chelation Therapy.
R. Bruce Martin
pp 690 - 690; DOI:
10.1021/jm00335a043
PDF

Issue 6


The Use of Substituent Constants in the Analysis of the Structure-Activity Relationship in Penicillin Derivatives
Corwin Hansch and A. Ruth Steward
pp 691 - 694; DOI:
10.1021/jm00336a001
PDF
Silicon Heterocyclic Compounds. III. Silicon-Substituted Spirobarbiturates
Ralph J. Fessenden, James G. Larsen, Marvin D. Coon, and Joan S. Fessenden
pp 695 - 698; DOI:
10.1021/jm00336a002
PDF
The Effect of Piperidinecarboxamide Derivatives on Isolated Human Plasma Cholinesterase. II. Variations in the Amide Function
James G. Beasley, Ronald P. Quintana, and Gretchen G. Nelms
pp 698 - 701; DOI:
10.1021/jm00336a003
PDF
Thyroxine Analogs. XI.1 Structural Isomers of 3,5,3′-Triiodo-DL-thyronine
Eugene C. Jorgensen and James A. W. Reid
pp 701 - 705; DOI:
10.1021/jm00336a004
PDF
Lower 2′-Alkylthio Analogs and Derivatives of Griseofulvin via a Mercaptanolysis Reaction
B. K. Koe and W. D. Celmer
pp 705 - 709; DOI:
10.1021/jm00336a005
PDF
Analogs of Spermine and Spermidine. I. Synthesis of Polymethylenepolyamines by Reduction of Cyanoethylated α,ω-Alkylenediamines
Mervyn Israel, Joan Samour Rosenfield, and Edward J. Modest
pp 710 - 716; DOI:
10.1021/jm00336a006
PDF
Compounds Derived from the Mannich Bases of β-Phenylpropiophenone
J. F. Cavalla, J. P. Marshall, and R. A. Selway
pp 716 - 721; DOI:
10.1021/jm00336a007
PDF
New Analgesic N-Substituted Carboxamides
Otis E. Fancher, Shin Hayao, Wallace G. Strycker, and L. F. Sancilio
pp 721 - 725; DOI:
10.1021/jm00336a008
PDF
Synthesis of Some N-Substituted 3,5-Dimethyl-4-piperidinols and Their Derivatives as Potential Analgesics
Norman J. Harper, Colin F. Chignell, and George Kirk
pp 726 - 728; DOI:
10.1021/jm00336a009
PDF
The Chemistry and Pharmacology of Some 4-Aminopiperidines and Their Derivatives
Norman J. Harper and Colin F. Chignell
pp 729 - 732; DOI:
10.1021/jm00336a010
PDF
Reductive Cyclization of 2-(Picolylidene)-1-indanones to Octahydroindeno[2,1-b]indolizine and Indenoisogranatanine
Joseph Sam, James Don England, and Dru W. Alwani
pp 732 - 734; DOI:
10.1021/jm00336a011
PDF
Synthesis and Pharmacology of Some β-Spiroindolenines and Indolines
Jerry A. Weisbach, Edward Macko, Nicholas J. De Sanctis, Michael P. Cava, and Bryce Douglas
pp 735 - 739; DOI:
10.1021/jm00336a012
PDF
Steroidal Carbamic Acid γ-Lactones
Eugene Farkas and John A. Swallow
pp 739 - 741; DOI:
10.1021/jm00336a013
PDF
The Synthesis and Myotrophic Activity of 1-Halo-4-methylestra-1,3,5(10)-trienes
G. W. Moersch, T. P. Culbertson, D. F. Morrow, E. L. Wittle, R. R. Humphrey, W. A. Neuklis, M. E. Butler, and M. M. Creger
pp 741 - 748; DOI:
10.1021/jm00336a014
PDF
6α-Fluoro- and 6α-Methyl-16α-fluoprorednisolones
B. J. Magerlein, F. H. Lincoln, R. D. Birkenmeyer, and F. Kagan
pp 748 - 751; DOI:
10.1021/jm00336a015
PDF
The Synthesis of 16α-Chloro Corticoids
Fred Kagan, Robert D. Birkenmeyer, and Barney J. Magerlein
pp 751 - 754; DOI:
10.1021/jm00336a016
PDF
Oxoestrapolyene Ketals as Antilipemic Agents
G. C. Buzby, R. A. Edgren, J. A. Fisher, G. A. Hughes, R. C. Jones, K. Ledig, T. W. Pattison, R. Rees, Herchel Smith, Leland L. Smith, D. M. Teller, and G. R. Wendt
pp 755 - 758; DOI:
10.1021/jm00336a017
PDF
Synthesis and Biological Activity of Isomers of N-[Bis(2-chloroethyl)aminobenzoyl]glutamic Acid
S.-C. J. Fu, H. Terzian, and S. Craven
pp 759 - 762; DOI:
10.1021/jm00336a018
PDF
Phosphorus Mustards. I. A New Class of Potential Antineoplastic Agents
T. P. Abbiss, A. H. Soloway, and V. H. Mark
pp 763 - 766; DOI:
10.1021/jm00336a019
PDF
α-Amidinium Thiosulfates (Bunte Salts) as Antiradiation Drugs
Ludwig Bauer and Karen Rover Sandberg
pp 766 - 768; DOI:
10.1021/jm00336a020
PDF
Aspects of the Chemical Mechanism of Complex Formation between Acetylcholinesterase and Acetylcholine-Related Compounds
B. Belleau and G. Lacasse
pp 768 - 775; DOI:
10.1021/jm00336a021
PDF
A Molecular Theory of Drug Action Based on Induced Conformational Perturbations of Receptors
B. Belleau
pp 776 - 784; DOI:
10.1021/jm00336a022
PDF
1-Aralkyl-4,4-dialkylpiperidines as Hypotensive Agents
T. C. Somers and G. J. Handley
pp 784 - 789; DOI:
10.1021/jm00336a023
PDF
Synthetic Antigonadotropins. II
H. H. Fox, J. T. Gibas, H. L. Lee, and A. Boris
pp 790 - 792; DOI:
10.1021/jm00336a024
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Pyrimidine Derivatives. VI. 2,4,5-Triamino-6-chloro- and -6-mercaptopyrimidine and Related Compounds
Mervyn Israel, Heljo Kangur Protopapa, Herbert N. Schlein, and Edward J. Modest
pp 792 - 799; DOI:
10.1021/jm00336a025
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Synthesis of Indomethacin Metabolites
R. G. Strachan, M. A. P. Meisinger, W. V. Ruyle, Ralph Hirschmann, and T. Y. Shen
pp 799 - 800; DOI:
10.1021/jm00336a026
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Regeneration of Antibiotic Activity by Deacetylation of N-Acetyl Derivatives of Deoxystreptamine-Containing Antibiotics
Gerald H. Wagman and Marvin J. Weinstein
pp 800 - 801; DOI:
10.1021/jm00336a027
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5,8-Isoquinolinediones. I. Synthesis of 5,8-Isoquinolinedione
P. K. Joseph and Madeleine M. Joullié
pp 801 - 803; DOI:
10.1021/jm00336a028
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Tumor Inhibitors. IV.1 Apocannoside and Cymarin, the Cytotoxic Principles of Apocynum cannabinum L.2
S. Morris Kupchan, Richard J. Hemingway, and Raymond W. Doskotch
pp 803 - 804; DOI:
10.1021/jm00336a029
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The Oral Progestational Activity of the 3-Ketals of Certain 17-Acetoxy- and 17-Alkylprogesterones
Martin J. Weiss, John F. Poletto, George R. Allen, Robert E. Schaub, and Ira Ringler
pp 804 - 806; DOI:
10.1021/jm00336a030
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Studies on Methylglyoxal Bis(guanylhydrazone)1 Analogs. III. Trifluoromethylglyoxal Bis(guanylhydrazone)2 and 1,2-Bis(guanidinoamino)propane3,4
Eugene G. Podrebarac and C. C. Cheng
pp 806 - 808; DOI:
10.1021/jm00336a031
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Pyrimidines. IV. 2-, 5-, and 2,5-Substituted Chloropyrimidines
Herman Gershon, Richard Braun, Alfred Scala, and Raymond Rodin
pp 808 - 811; DOI:
10.1021/jm00336a032
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Sulfanilamidoquinazolines
Tellis A. Martin, Allan G. Wheeler, Robert F. Majewski, and John R. Corrigan
pp 812 - 814; DOI:
10.1021/jm00336a033
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Reactions between Orthoesters and Organic Nitrogen Compounds. VI.1 Arylhydrazines
C. Runti and C. Nisi
pp 814 - 816; DOI:
10.1021/jm00336a034
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Fluorine-Containing Potential Anticancer Agents. III.1a Syntheses of Some Trifluoromethylpyrazolo[3,4-d]pyrimidines1b
Shoji Inoue, Hideo Nagano, Edward A. Nodiff, and Andrew J. Saggiomo
pp 816 - 818; DOI:
10.1021/jm00336a035
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Aminostyrylquinolines
Carl Tabb Bahner, Lydia Moore Rives, and Charles Breder
pp 818 - 819; DOI:
10.1021/jm00336a036
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6-(5-Nitro-2-furyl)-as-triazine-3,5(2H,4H)-dione. A Potential Urinary Tract Antibacterial
Kenyon Hayes
pp 819 - 820; DOI:
10.1021/jm00336a037
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Synthesis of Tripeptides of α-Aminoisobutyric Acid
J. Friedrich Diehl and Ellen A. Young
pp 820 - 821; DOI:
10.1021/jm00336a038
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3,6-Bis-p-dimethylaminobenzylidene-2,5-diketopiperazine
Carl Tabb Bahner and William Longmire
pp 821 - 821; DOI:
10.1021/jm00336a039
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The Preparation of 4-Substituted Benzothiadiazines
E. Magnien, W. Tom, and W. Oroshnik
pp 821 - 823; DOI:
10.1021/jm00336a040
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The Synthesis of N-Substituted 2-Aminoethanethiosulfuric Acids
Daniel L. Klayman and W. Franklin Gilmore
pp 823 - 824; DOI:
10.1021/jm00336a041
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Aminooxyacetic Acid Derivatives
Alfred Richardson
pp 824 - 826; DOI:
10.1021/jm00336a042
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Agents Affecting Lipid Metabolism. XII. N,N′-Disubstituted Cyclohexane-1,4-bis(methylamines)
Leslie G. Humber
pp 826 - 830; DOI:
10.1021/jm00336a043
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Synthesis of 3,5,3′,5′-Halogen-Substituted Thyropropionic Acids
Teruo Matsuura
pp 830 - 831; DOI:
10.1021/jm00336a044
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Synthesis of 2,2-Diphenyl-5-cyanocyclopentanone
Stuart S. Kulp and Stanley A. Iobst
pp 831 - 831; DOI:
10.1021/jm00336a045
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Some 2,3-Disubstituted Quinazolones
K. Kishor, R. Kumar, and Surendra S. Parmar
pp 831 - 832; DOI:
10.1021/jm00336a046
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9-Thienylanthracenes
Frank A. Vingiello, Sih-Gwan Quo, Perry Polss, and Paul Henson
pp 832 - 833; DOI:
10.1021/jm00336a047
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The Neomycins and Related Antibiotics.
Theodore H. Haskell
pp 833 - 833; DOI:
10.1021/jm00336a048
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Experimental Chemotherapy. Volume II. Chemotherapy of Bacterial Infections. Part I.
Alfred Burger
pp 833 - 833; DOI:
10.1021/jm00336a049
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Metabolic Inhibitors--A Comprehenisive Treatise.
Alfred Burger
pp 833 - 834; DOI:
10.1021/jm00336a050
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Absorption and Distribution of Drugs.
Alfred Burger
pp 834 - 834; DOI:
10.1021/jm00336a051
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Interpretation of Mass Spectra of Organic Compounds.
Norbert Neuss
pp 834 - 834; DOI:
10.1021/jm00336a052
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The Chemistry and Therapy of Disorders of Voluntary Muscles.
Alfred Burger
pp 834 - 834; DOI:
10.1021/jm00336a053
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Molecular Pharmacology. The Mode of Action of Biologically Active Compounds. Volume I.
Alfred Burger
pp 834 - 835; DOI:
10.1021/jm00336a054
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Drugs in Our Society.
Alfred Burger
pp 835 - 835; DOI:
10.1021/jm00336a055
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Additions and Corrections - Reaction of 6-Chloro-2-chloromethyl-4-phenylquinazoline 3-Oxide with Dimethylamine
S. Farber, H. M. Wuest, and R. I .Meltzer
pp 835 - 835; DOI:
10.1021/jm00336a056
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Additions and Corrections - Central Nervous System Depressants. VI. Polymethoxyphenyl Esters and Amides.
R. B. Moffett
pp 835 - 835; DOI:
10.1021/jm00336a600
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Additions and Corrections - Synthesis and Anabolic Activity of 3-Methylene and 3-Methylsteroids of the Androstane and 19-Norandrostane Series.
K. Irmscher, H.-G. Kraft, and K. Brückner
pp 835 - 835; DOI:
10.1021/jm00336a601
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